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KMID : 0361120020160020238
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Korean Journal of Transplantation
2002 Volume.16 No. 2 p.238 ~ p.243
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Donor Safety in Living Donor Liver Transplantation Using Right Lobe
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허훈/Hoon Hur
김동구/최성호/문인성/이명덕/김인철/Dong Goo Kim/Sung Ho Choi/In Sung Moon/Myung Duk Lee/In Chul Kim
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Abstract
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Purpose: Right lobe donation is technically more difficult and need to define surgical technique and has more risk for surgical complication. Right lobe donation usually matched graft size but safety of donor is major concern. In this
paper,
we
reviewed our experience of donor hepatectomy using right lobe in regarding to safe of our donor operations, retrospectively.
Methods: Retrospective analysis of 42 donor operations for adult LDLT using right lobe was performed. We observed the patient characteristics, the operative findings, peak liver enzymes (AST, ALT, bilirubin) as donor risk and mortality,
morbidity.
Results: The peak value of liver enzymes in the group of less the 30% of remained liver were significantly higher than the group of more than 30% of remained liver and these values could induced the risk on donor. The postoperative peak
value of
liver enzymes were increased according to degree of fatty change especially in case of more than 10% fatty change even without significance. We observed the liver regeneration on postoperative 3 months and the regeneration of liver volume on
postoperative 3 months was about two times compare to preoperative value and the regenerative activity was more increased in the group of less amount of remained volume. There was no donor mortality and most important complication was biliary
complication, in which were biliary injury, bile leakage and biliary stricture.
Conclusion: Right lobectomy for donor operation requires a meticulous surgical technique to minimize donor morbidity. Right lobectomy can be performed safely with minimal risk in case of careful donor selection that the remained liver
volume
exceed 30% of the total liver volume and the liver of minimal fatty change.
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KEYWORD
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